What is Resveratrol?

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by Jilly Peter

Resveratrol is a natural phytolexin produced by the plants when under attack from pathogens like bacteria and fungi. Resveratrol is sold as a nutritional chemical supplement. Chemically resveratrol is the phytolexin that can be derived from Japanese Knotweed. Primarily it is an essential component in th berries and grapes.

Resveratrol is one of the most potent content found in the skin of red grapes and is a constituent of red wine. Experiments have shown that resveratrol treatment extended the life of fruit flies, nematode worms and short living fish but it did not increase the life span of certain mammals.

Resveratrol (3,5,4′-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase.

It exists as two geometric isomers: cis- (Z) and trans- (E), with the trans-isomer shown in the top image. The trans- form can undergo isomerisation to the cis- form when exposed to ultraviolet irradiation.

Trans resbveratrol is a very stable compound with accelerated stability conditions of 75% humidity and 40 degrees C in normal air preesure. Resveratrol content also stayed stable in the skins of grapes and pomace taken after fermentation and stored for a long period.

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